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TARTRATE RESISTANT ACID PHOSPHATASE
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DeCS
Descriptor
English
:
Tartrate-Resistant Acid Phosphatase
Descriptor
Spanish
:
Fosfatasa Ácida Tartratorresistente
Descriptor
Portuguese
:
Fosfatase Ácida Resistente a Tartarato
Synonyms
English
:
AcPase V
Acid Phosphatase V
TRAP Type 5 AcPase
TRAcP
Tartrate-Resistant Acid Phosphatase Type 5
Type 5 Acid Phosphatase
Uteroferrin
Acid Phosphatase, Tartrate-Resistant
Phosphatase V, Acid
Phosphatase, Tartrate-Resistant Acid
Tartrate Resistant Acid Phosphatase
Tartrate Resistant Acid Phosphatase Type 5
V, AcPase
V, Acid Phosphatase
Tree Number:
D08.811.277.352.650.025.500
D08.811.277.352.650.625.862
Definition
English
:
One of several acid phosphatases in
humans
, other
mammals
,
plants
, and a few prokaryotes. The protein fold of
tartrate-resistant acid phosphatase
(TRAP) resembles that of the
catalytic domain
of plant purple
acid phosphatase
and other serine/threonine-protein phosphatases that also contain a metallophosphoesterase domain. One gene produces the various forms which include purple acid phosphatases from
spleen
and other
tissues
.
Tartrate-resistant acid phosphatase
is a biomarker for pathological states in which it is over-expressed. Such conditions include
GAUCHER DISEASE
;
HODGKIN DISEASE
;
BONE RESORPTION
; and
NEOPLASM METASTASIS.
History Note
English
:
2017 (1995)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56474
Unique Identifier:
D000071681
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS